The story starts with an American visiting the Kalindi Temple at night. There he sees the priest of the temple in a horrific state – he had slit his body with a scythe and had written ‘Om’ on his body. The man, horrified by what he is seeing, flees from there. The story then shifts to a model in her early 20s, Nandita (Kangana Ranaut) who is in love with Yash, (Adhyayan Suman) a director and host of the reality show “Andhvishwas” a show dealing with various superstitions of Tanuja Twins ghosts mirror and tantric voodoos. Yash gifts Nandita an apartment where they start living and they love each other, in the meantime Nandita gets pregnant.
One evening, Nandita encounters Prithvi (Emraan Hashmi), an aspiring artist who is in search of his masterpiece. Prithvi tells Nandita that he made a sketch 4 months ago of a girl, who is actually Nandita. He also shows her a painting where she is lying with her wrist slit. He warns her of any type of danger. Regardless, Nandita accidentally slits her wrist due to an unknown ghostly attack on her in the bathroom. Prithvi saves her and admits her to a hospital. Yash arrives to the hospital and comes to know about her pregnancy and also her miscarriage due to excessive bleeding. She complains to Yash about Prithvi, and Yash gets him arrested, though he is released later on.
Meanwhile, at Kalindi, the same American, David Cooper (J. Brandon Hill), who is the Kalindi chemical plant owner, commits suicide by hanging himself after writing on the wall of his bathroom, “Tum ashudh ho, andar sey sadh chuke ho” (You are impure, you are rotten from inside), with his blood. The inspector investigating the suicide is severely affected by it. Back at his home, Prithvi makes another picture of Nandita getting mobbed. He runs to a fashion show where Nandita is performing, and witnesses her being possessed and attacking a spiritual guru attending the show. She then says the same lines, “Tum ashudh Ho, andar sey sadh chuke ho”, to the guru. Prithvi rushes to her rescue, but is prevented by the guards. Nandita is taken away from the guru and audience. The guru later appears on TV, claiming she had been possessed. Coming to know about everything, Yash has her publicly apologise to everyone, and declares that she has mental problems.